Fourleaf Milkweed
Asclepias quadrifolia
Found in moist to dryish forests and forest margins, most common on mafic and calcareous substrates. Weakley, Flora of the Southeastern United States (2025), Northern Tier edition What its natural habitat tells you
Native to Virginia. How scores work Is it native here?
Profile 100%
- Height
- 1–3 feet
- Spread
- 1.75–2 feet
- Light
- Full sun, Partial shade
- Soil moisture
- Dry to average
Space about 2 ft apart from its recorded spread, about 25 per 100 sq ft. Enter your bed size for a count
Will it fit your yard?
At a glance
- Life cycle
- Perennial
- Leaves
- Deciduous
- Bloom
- Spring and summer
- Fruiting season
- May to November
Recorded in 55 Virginia counties.
Natural habitats
Places it grows wild. Not a planting requirement. Each habitat page lists the plants and wildlife also found there.

Forest or woodland where the source does not say how moist or dry.
Who uses this plant?
13CaterpillarsGenus host records with ranges including VA
Genus host records with ranges including VA · Asclepias
- Danaus plexippusMonarch
- Cycnia collarisUnexpected Cycnia
- Cycnia teneraDelicate Cycnia, Dogbane Tiger Moth
- Euchaetes egleMilkweed Tussock Moth or Milkweed Tiger Moth
- Hyalophora cecropiaCecropia Silkmoth, Cecropia Moth
- Melanchra adjunctaHitched Arches
- Papaipema nebrisStalk Borer
- Platynota flavedanaBlack-Shaded Platynota
- Pyrrharctia isabellaIsabella Tiger Moth, Banded Woolybear
- Spodoptera frugiperdaFall Armyworm Moth
Show all 13
- Strymon melinusGray Hairstreak
- Trichordestra legitimaStriped Garden Caterpillar Moth
- Pygarctia eglenensis
59BeesSoutheastern regional records
Southeastern regional records · Asclepias
Individual names are not available yet.
Noori, Seltmann & Orr 2026, A curated and integrated dataset for exploring global bee-plant interactions (GloBI), Zenodo, CC BY 4.0
1BirdsRecorded genus food-resource interactions; not a state feeding claim
Recorded genus food-resource interactions; not a state feeding claim · Asclepias
- Ortalis vetulaPlain Chachalaca
Direct food only: birds recorded eating this genus across North America. Caterpillars on host plants also feed nesting birds. NC Native Plant Society: butterfly gardening
No records yet · Ants · Beetles · Flies · Adult butterflies / moths · Other wasps · Other insects
Plant details
- Family
- Apocynaceae
- Hardiness
- Zones 5a–8b
- Soil pH
- Acidic to neutral
- Flower color
- Pink or white
- Fruit begins
- May
- Fruit ends
- November
Safety has not been reviewed for this plant; check toxicity and thorns before planting.
Growing sources and scope
- Bloom · “Spring and summer” · NC Extension Plant Toolbox
- Flower color · “Pink or white” · NC Extension Plant Toolbox
- Fruit begins · “May” · Weakley, Flora of the Southeastern United States (2025), Carolinas & Georgia edition · Carolinas and Georgia
- Fruit ends · “November” · Weakley, Flora of the Southeastern United States (2025), Carolinas & Georgia edition · Carolinas and Georgia
- Hardiness · “Zones 5a–8b” · NC Extension Plant Toolbox
- Height · “1–3 feet” · NC Extension Plant Toolbox (ranked first; Tennessee Smart Yards, Weakley, Flora of the Southeastern United States (2025), Carolinas & Georgia edition differ)
- Leaves · “Deciduous” · NC Extension Plant Toolbox
- Life cycle · “Perennial” · NC Extension Plant Toolbox
- Light · “Full sun (6 or more hours of direct sunlight a day); Partial shade (direct sunlight only part of the day, 2-6 hours)” · NC Extension Plant Toolbox (ranked first; Tennessee Smart Yards differs)
- Soil · “Good drainage; Occasionally dry” · NC Extension Plant Toolbox (ranked first; Tennessee Smart Yards differs)
- Soil pH · “Acidic to neutral” · NC Extension Plant Toolbox
- Spread · “1.75–2 feet” · NC Extension Plant Toolbox
Conservation status
| Virginia rank | S5 |
|---|---|
| Global rank | G5 |
| VA status | Not verified |
| Federal status | Not verified |
Will it fit your yard?
Check this plant against your county, sun and soil moisture. Conditions are checked in your browser.
Sources
- Digital Atlas of the Virginia Flora
- USDA PLANTS
- Vascular Plants of North Carolina (NC Natural Heritage Program)
- Weakley, Flora of the Southeastern United States (2025), Carolinas & Georgia edition
- NatureServe Explorer
- Shropshire & Tallamy 2025, Lepidoptera of North America north of Mexico, ZooKeys 1261 (ODbL)
- Noori, Seltmann & Orr 2026, A curated and integrated dataset for exploring global bee-plant interactions (GloBI), Zenodo, CC BY 4.0
- Smith, Bachelder, Russell, Morales, Mosher & Seltmann 2024, Bee-Specialization-Modeling v0.6.1 (specialist host table compiled from J. Fowler's pollen specialist bee lists), Zenodo, CC BY 4.0
- Hurlbert, Olsen, Sawyer & Winner 2021, Avian Diet Database, Scientific Data 8: 260 (CC0)
- Narango, Tallamy & Shropshire 2020, Few keystone plant genera support the majority of Lepidoptera species, Nature Communications

